Title
Trajectories of Spiritual Well-being and Symptoms Over Time among Adults with Cancer

Description
Trajectories of Spiritual Well-being and Symptoms Over Time among Adults with Cancer

Objective
Primary:
-Examine SWB over time (for one year after treatment initiation) among adults with cancer.
-Examine SPADE symptoms (intensity, distress, and interference) over time (for one year after treatment initiation) among adults with cancer.
-Examine relationships between SWB and SPADE symptoms (intensity, distress, and interference) over time (for one year after treatment initiation) among adults with cancer.

Treatment Participants will complete surveys at baseline , then at 3-, 6-, and 12 months post treatment initiation. The baseline data collection target is within 14 days of initiating cancer-directed treatment, with an allowable window of up to 60 days. For participants receiving cytotoxic chemotherapy, baseline completion will be prioritized prior to the first infusion or within 3 days after infusion whenever feasible, to minimize completion during the period when treatmentrelated symptoms are often most severe. Chemotherapy cycle number and day-in-cycle at the time of survey completion will be recorded and incorporated in analyses to account for within-cycle variability.

Key Eligibility Inclusion criteria are:
-18+ years old.
-Diagnosis of breast, colorectal, prostate, or lung cancer.
-Beginning a new line of systemic cancer-directed treatment with curative intent (chemotherapy, endocrine therapy, targeted therapy, and/or immunotherapy, with or without other treatments).
-Able to read, write, and speak in English.

Applicable Disease Sites
Anal; Breast; Colon and Rectum; Lung; Prostate

Participating Institutions
UW Health Eastpark Medical Center; UW Health University Hospital